If you need a simple dinner that is filling, packed with protein, and full of flavor, this High Protein Chicken Broccoli Casserole is a great choice. It comes together with everyday ingredients and bakes into a creamy, cheesy meal that is perfect for busy weeknights or meal prep. Every bite has tender chicken, fresh broccoli, creamy cottage cheese, and melted cheddar cheese for a comforting meal that also helps you reach your protein goals.
Servings: 6
Prep Time: 15 minutes
Cook Time: 35 minutes
Total Time: 50 minutes
Why I Love This Recipe
I started making this casserole when I wanted something comforting without feeling heavy. Most casseroles are loaded with cream and not much protein, so I wanted a version that was both satisfying and nutritious. Swapping in cottage cheese and Greek yogurt made the sauce creamy while adding a big protein boost. The first time I made it, I was surprised by how rich and cheesy it tasted even with lighter ingredients. Now it has become one of those recipes I keep coming back to because it is easy, dependable, and always leaves great leftovers.
Here’s why I keep making it:
- It packs over 35 grams of protein in every serving.
- The sauce is creamy without using canned soup.
- Fresh broccoli stays tender with a little bite.
- It reheats beautifully for lunches.
- Everything comes together in one baking dish.
- It feels like comfort food while still being balanced.
What You’ll Need
- 3 cups cooked chicken breast, shredded (about 1½ pounds)
- 4 cups broccoli florets, chopped into bite-sized pieces
- 1 cup low-fat cottage cheese
- 1 cup plain non-fat Greek yogurt
- 1 cup shredded sharp cheddar cheese, divided
- ½ cup grated Parmesan cheese
- 1 small onion, finely diced
- 2 cloves garlic, minced
- 1 teaspoon onion powder
- 1 teaspoon garlic powder
- 1 teaspoon smoked paprika
- ½ teaspoon black pepper
- ½ teaspoon salt
- ½ teaspoon dried thyme
- 1 tablespoon olive oil
- 2 tablespoons chopped fresh parsley (optional for garnish)
Why This Recipe Works (Quick Science)
The protein comes from several sources instead of just the chicken. Cottage cheese and Greek yogurt add protein while also creating a creamy sauce. As the casserole bakes, the proteins in the dairy gently firm up, making the filling thick without needing flour or canned soup. Broccoli releases a little moisture as it cooks, helping keep the chicken juicy while the cheddar melts into a smooth, flavorful topping.
Pro Tips
- Pat the broccoli dry after washing so the casserole stays creamy.
- Use freshly shredded cheddar for the smoothest melt.
- Let the casserole rest for 10 minutes after baking so it slices neatly.
- Taste the sauce before mixing everything together and adjust the seasoning if needed.
- Rotisserie chicken works well when you need to save time.
Tools You’ll Need
- 9×13-inch baking dish
- Large mixing bowl
- Medium bowl
- Whisk
- Rubber spatula
- Cutting board
- Chef’s knife
- Measuring cups
- Measuring spoons
Substitutions and Variations
- Swap cheddar for mozzarella, Monterey Jack, or Colby Jack.
- Use cooked turkey instead of chicken.
- Replace broccoli with cauliflower.
- Add cooked mushrooms for extra flavor.
- Stir in cooked brown rice or quinoa for a heartier casserole.
- Use full-fat Greek yogurt if preferred.
Make Ahead Tips
Mix the casserole up to one day ahead and cover tightly before refrigerating. Bake when ready to serve, adding about 5 extra minutes if baking straight from the refrigerator. You can also freeze the unbaked casserole for up to 2 months. Thaw overnight before baking.
Recipe
Step 1: Prepare the Oven and Baking Dish
Preheat the oven to 375°F (190°C). Lightly grease a 9×13-inch baking dish with 1 tablespoon olive oil.
Step 2: Make the Creamy Sauce
In a large mixing bowl, whisk together 1 cup low-fat cottage cheese, 1 cup plain non-fat Greek yogurt, ½ cup grated Parmesan cheese, ½ cup of the shredded sharp cheddar cheese, 1 teaspoon onion powder, 1 teaspoon garlic powder, 1 teaspoon smoked paprika, ½ teaspoon salt, ½ teaspoon black pepper, and ½ teaspoon dried thyme until smooth and creamy.
Step 3: Add the Main Ingredients
Fold 3 cups shredded cooked chicken breast, 4 cups chopped broccoli florets, and 1 small finely diced onion into the creamy sauce. Stir until every piece is evenly coated.
Step 4: Fill the Baking Dish
Spread the mixture evenly into the prepared baking dish. Sprinkle the remaining ½ cup shredded sharp cheddar cheese evenly across the top.
Step 5: Bake
Bake for 30 to 35 minutes until the casserole is hot throughout and the cheese is melted and lightly golden.
Step 6: Rest and Serve
Let the casserole rest for 10 minutes before serving. Sprinkle with 2 tablespoons chopped fresh parsley if using, then serve warm.
Leftovers and Storage
Store leftovers in an airtight container in the refrigerator for up to 4 days. Reheat individual portions in the microwave for 2 to 3 minutes or warm larger portions in a 350°F oven until heated through. Freeze cooled portions for up to 2 months and thaw overnight before reheating.
Common Mistakes
- Using watery broccoli can make the casserole thin.
- Overbaking can dry out the chicken.
- Skipping the resting time makes the casserole fall apart when serving.
- Using pre-shredded cheese may give the sauce a less creamy texture.
- Forgetting to season the sauce can make the casserole taste flat.
What to Serve With
- Simple green salad with lemon vinaigrette
- Roasted sweet potatoes
- Garlic green beans
- Brown rice
- Quinoa
- Whole wheat dinner rolls
- Fresh fruit salad
Macros Information
Per serving (approximately):
- Calories: 365
- Protein: 38g
- Carbohydrates: 11g
- Fat: 18g
- Fiber: 3g
- Sugar: 5g
Nutrition values are estimates and may vary depending on the ingredients used.
FAQ
Can I use rotisserie chicken?
Yes. Simply shred the meat and measure out 3 cups.
Can I use frozen broccoli?
Yes. Thaw it first and pat it dry to remove extra moisture.
Can I make this casserole ahead of time?
Yes. Assemble it up to one day ahead, cover, refrigerate, and bake when ready.
Can I freeze it?
Absolutely. Freeze before or after baking for up to 2 months.
How do I know when it’s done?
The casserole should be bubbling around the edges, and the cheese on top should be melted and lightly golden.
Conclusion
This High Protein Chicken Broccoli Casserole proves that comfort food can also be nourishing and satisfying. It is creamy, cheesy, packed with protein, and simple enough for any night of the week. Whether you are making it for meal prep or sharing it with family and friends, this casserole is one you’ll want to make again and again. Give it a try, then come back and leave a comment with your experience or any questions. I’d love to hear how it turned out for you.
